HG-6-63-01

SKU: orb2665295

Description

HG-6-63-01 is a potent and selective type II RET tyrosine kinase inhibitor. It effectively suppresses the proliferation and signaling of RET-driven cancer cells, including those harboring oncogenic mutants like C634R and M918T, making it a valuable research tool for investigating RET-dependent cancers in vitro.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2177298-99-4
• MW: 582.06
• Formula: C₃₁H₃₁ClF₃N₅O
• SMILES: O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(CC)CC2)C3=CC=C(C(C=CC=4C=NC=5NC=CC5C4Cl)=C3)C
• Target: c-RET

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

67348173