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HF50731

SKU: orb1687898

Description

HF50731 is a potent and selective CXCR4 antagonist with high binding affinity (IC50: 19.8 nM). It effectively inhibits CXCR4-mediated functions, including calcium mobilization and cell migration, and potently blocks HIV-1 entry via this co-receptor (IC50: 1.5 nM). This small molecule is a valuable research tool for studying oncology, immunology, and HIV pathogenesis in experimental models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

CAS Number2484771-19-7
MW414.67
FormulaC26H46N4
SMILESC(NCCCNC1CCCCC1)C2=CC=C(CNCCCNC3CCCCC3)C=C2
TargetCXCR,HIV Protease,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information