Herbacetin

SKU: orb1301293

Description

Herbacetin is a bioactive flavonoid that induces apoptosis in HepG2 cells via ROS generation and PI3K/Akt pathway inhibition. It also suppresses HGF-induced migration in MDA-MB-231 breast cancer cells by blocking c-Met and Akt phosphorylation, making it a candidate for research in oncology and cell signaling pathways.

Research Area

Signal Transduction

Key Properties

• CAS Number: 527-95-7
• MW: 302.24
• Purity: 99.51% (May vary between batches)
• Formula: C₁₅H₁₀O₇
• SMILES: Oc1ccc(cc1)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O
• Target: c-Met/HGFR,Akt
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.62 mM);DMSO:150 mg/mL (496.29 mM)

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Herbacetin, HGFR, cMet/HGFR, c-Met, cMet, Akt

Compound Identifiers

PubChem CID

5280544