HER2-IN-15

SKU: orb3133980

Description

HER2-IN-15 (Compound 1) is a HER2 inhibitor that effectively targets the YVMA HER2 exon 20 insertion mutation (HER2 YVMA) with an IC50 of less than 200 nM. It also inhibits the proliferation of BaF3 cells with the HER2 YVMA mutation, achieving an IC50 of under 200 nM, and contributes to the improvement of non-small cell lung cancer (NSCLC).

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• Formula: C₂₈H₂₉N₉O₂
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR