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HER2-IN-14

SKU: orb1982257

Description

HER2-IN-14 (Compound 34) is a small molecule inhibitor with potent activity against HER2 (IC50 = 18 nM) and weaker activity against wild-type EGFR (IC50 = 6.3 µM). It serves as a valuable research tool for investigating HER2-driven cancers in both cellular and biochemical assay systems.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2414056-35-0
MW568.96
FormulaC26H23ClF2N8O3
SMILESO(C=1C=2C(NC3=CC(Cl)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@@H]6C(F)(F)CN(C)CC6
TargetOthers,EGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

HER2-IN-14 (orb1982257)

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