HER2-IN-13

SKU: orb1982258

Description

HER2-IN-13 (Compound 33) is a potent, dual-activity small molecule inhibitor, demonstrating high potency against HER2 (IC50 = 8 nM) and activity against wild-type EGFR (IC50 = 0.40 µM). This profile supports its application in biochemical and cellular research for investigating HER2-driven and EGFR-related oncology pathways in vitro.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2414056-34-9
• MW: 568.96
• Formula: C₂₆H₂₃ClF₂N₈O₃
• SMILES: O(C=1C=2C(NC3=CC(Cl)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@H]6C(F)(F)CN(C)CC6
• Target: Potassium Channel,Others,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146510153