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HER2-IN-13

SKU: orb1982258

Description

HER2-IN-13 (Compound 33) is a potent, dual-activity small molecule inhibitor, demonstrating high potency against HER2 (IC50 = 8 nM) and activity against wild-type EGFR (IC50 = 0.40 µM). This profile supports its application in biochemical and cellular research for investigating HER2-driven and EGFR-related oncology pathways in vitro.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2414056-34-9
MW568.96
FormulaC26H23ClF2N8O3
SMILESO(C=1C=2C(NC3=CC(Cl)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@H]6C(F)(F)CN(C)CC6
TargetPotassium Channel,Others,EGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

HER2-IN-13 (orb1982258)

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