Hepatitis B virus (adr) S-HBsAg Protein, His Tag

SKU: orb3158087

Description

Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). The hepatitis B virus attacks the liver and can cause both acute and chronic disease that puts people at high risk of death from cirrhosis and liver cancer. The virus is most commonly transmitted from mother to child during birth and delivery, as well as through contact with blood or other body fluids. Hepatitis B virus (HBV) is a member of the hepadnavirus family. The virus particle (virion) consists of an outer lipid envelope and an icosahedral nucleocapsid core composed of core protein. The nucleocapsid encloses the viral DNA and a DNA polymerase that has reverse transcriptase activity. The outer envelope contains embedded proteins that are involved in viral binding of, and entry into, susceptible cells. The surface antigens (HBsAg) decorating the lipid envelope of HBV is produced in excess during the life cycle of the virus, and its presence in blood indicates current hepatitis B infection.

Research Area

Infectious Disease & Virology

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.3 kDa. The protein migrates as 23-25 kDa and 42-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Key Properties

• Expression System: E. coli
• Target: Hepatitis B surface antigen/HBsAg (HBV)
• Reactivity: Virus
• Tag: C-10×His
• Expression Region: Met 1 - Ile 226
• Conjugation: Unconjugated
• MW: 27.3 kDa
• Purity: 90%

Storage & Handling

• Storage: -70°C
• Form/Appearance: Liquid
• Buffer/Preservatives: 50 mM HEPES, 150 mM NaCl, pH 7.5
• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Hepatitis B surface antigen/HBsAg (HBV)

UniProt

P30019

RefSeq:P30019