Henatinib maleate

SKU: orb3174518

Description

Henatinib maleate is an orally active small-molecule multi-kinase inhibitor. It inhibits the activity of VEGFR-2, c-kit, and PDGFR with IC50 values of 0.6 nM, 3.3 nM, and 41.5 nM, respectively. Henatinib maleate significantly suppresses VEGFR-2 phosphorylation and its downstream signaling pathways, and it possesses extensive antitumor activity.

Key Properties

• CAS Number: 1239269-52-3
• MW: 584.6
• Formula: C₂₉H₃₃FN₄O₈
• SMILES: C(=C\C(O)=O)\C(O)=O.C(=C\1/C=2C(NC1=O)=CC=C(F)C2)\C3=C(C)C4=C(N3)CCCN(C[C@@H](CN5CCOCC5)O)C4=O
• Target: VEGFR,PDGFR,c-Kit

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

VEGFR,PDGFR,c-Kit