Helenalin

SKU: orb1707223

Description

Helenalin is an anti-inflammatory sesquiterpene lactone that selectively inhibits NF-κB by alkylating cysteine residues in the p65 subunit, blocking its DNA binding. This mechanism has been utilized in vitro to study inflammatory signaling pathways and has shown activity in cellular models of inflammation.

Research Area

Signal Transduction

Key Properties

• CAS Number: 6754-13-8
• MW: 262.31
• Purity: >98%
• Formula: C₁₅H₁₈O₄
• SMILES: [H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](O)[C@]1([H])C(=C)C(=O)O2
• Target: Telomerase
• Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23205