Hederacolchiside E

SKU: orb1297345

Description

Hederacolchiside E is a neuroprotective agent with antioxidant properties, demonstrated to mitigate oxidative stress in Alzheimer's disease models. It inhibits linoleic acid lipid peroxidation in vitro and shows potential for research in neurodegenerative disorders involving oxidative damage.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Neuroscience

Key Properties

• CAS Number: 33783-82-3
• MW: 1367.52
• Purity: 99.78%
• Formula: C₆₅H₁₀₆O₃₀
• SMILES: C(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@]45[C@](C=6[C@@](C)(CC4)[C@@]7(C)[C@](CC6)([C@]8(C)[C@@](CC7)(C(C)(C)[C@@H](O[C@H]9[C@H](O[C@H]%10[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O%10)[C@@H](O)[C@@H](O[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)CO9)CC8)[H])[H])(CC(C)(C)CC5)[H]
• Target: Apoptosis,Beta Amyloid,ROS,Parasite

Bioactivity

• In Vitro:
  Hederacolchiside exhibited a strong total antioxidant activity. At the concentration of 75 pg/mL, these saponins showed 88% inhibition on lipid peroxidation of linoleic acid emulsion.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ROS, β Amyloid, βAmyloid, bAmyloid, b Amyloid, Beta Amyloid, BetaAmyloid, Hederacolchiside E

Compound Identifiers

PubChem CID

101358459