Hederacolchiside A1

SKU: orb1304726

Description

Hederacolchiside A1 (Raddeanoside R13) is a bioactive saponin demonstrating potent anti-leishmanial activity by disrupting parasite membrane integrity and potential. It also exhibits antiproliferative effects against cancer cell lines, including melanoma, by inducing apoptosis via modulation of the PI3K/Akt/mTOR pathway, as shown in in vitro studies.

Research Area

Cell Biology, Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 106577-39-3
• MW: 897.1
• Purity: 99.54%
• Formula: C₄₇H₇₆O₁₆
• SMILES: [H][C@@]1(O[C@H]2CO[C@@]([H])(O[C@H]3CC[C@@]4(C)[C@@]([H])(CC[C@]5(C)[C@]4([H])CC=C4[C@]6([H])CC(C)(C)CC[C@@]6(CC[C@@]54C)C(O)=O)C3(C)C)[C@H](O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
• Target: Akt,mTOR,MEK,PI3K,Parasite,ERK,Apoptosis
• Solubility: DMSO:83.3 mg/mL (92.85 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.68 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ERK, Hederacolchiside A 1, Hederacolchiside A1, Hederacolchiside A-1, Mammalian target of Rapamycin, MEK, Parasite, Inhibitor, mTOR, inhibit, Akt, Apoptosis, Phosphoinositide 3-kinase, PI3K, Protein kinase B, PKB, Raddeanoside R13

Compound Identifiers

PubChem CID

11622076