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Heat Shock Protein Inhibitor II

SKU: orb1693377

Description

Hsp inhibitor II is the bioactive benzylidene lactam form that suppresses inducible Hsp synthesis, including Hsp105, Hsp72, and Hsp40. It reduces tumor thermotolerance in vivo and inhibits thermotolerance development in vitro. Furthermore, it synergizes with amphotericin B to enhance antifungal efficacy against both susceptible and resistant A. fumigatus strains.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1859-42-3
MW217.22
FormulaC12H11NO3
SMILESC(C=1C=C2C(=CC1)OCO2)=C3C(=O)NCC3
TargetOthers,HSP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information