HEAL-116

SKU: orb3173080

Description

HEAL-116 is a potent, specific, and orally active inhibitor of the type 1 3β-hydroxysteroid dehydrogenase (3βHSD1), with an IC50 value of 1.18 μM and a KD value of 1.32 μM. It inhibits both the metabolism of DHEA and DHEA-induced expression of target genes as well as cell proliferation. HEAL-116 is applicable in cancer research, including studies on prostate cancer.

Research Area

Metabolism Research

Key Properties

• CAS Number: 3059767-85-7
• MW: 371.82
• Formula: C₂₀H₁₈ClNO₄
• SMILES: O=C1C(=COC2=CC(O)=CC=C12)C=3C=CC(Cl)=C(C3)CN4CCOCC4
• Target: Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Dehydrogenase