HDM2004

SKU: orb3211020

Description

HDM2004 is a selective, orally active HPK1 inhibitor that can cross the blood-brain barrier, with an IC50 of 1.89 nM. It exhibits anticancer activity against colon cancer and demonstrates synergistic effects in homologous mouse models when combined with anti-PD-L1 treatment. HDM2004 can be utilized in colon cancer research.

Key Properties

• CAS Number: 2953016-30-1
• MW: 485.62
• Formula: C₂₈H₃₅N₇O
• SMILES: C(C)N1CCC(N2C=C(C=3C=4C(NC3)=NC=C(N4)C5=CC=C(C=C5)N6C[C@@H](C)O[C@H](C)C6)C=N2)CC1
• Target: MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

MAPK