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HDACs/EZH2-IN-1

SKU: orb2802175

Description

HDACs/EZH2-IN-1 (Compound 22a) is a potent dual inhibitor of HDAC1/6 and EZH2, including the Y641N mutant. It demonstrates anti-proliferative, pro-apoptotic, and differentiation-inducing effects in EZH2-mutant diffuse large B-cell lymphoma and acute myeloid leukemia cell models in vitro.

Research Area

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Images & Validation

Key Properties

MW626.54
FormulaC29H36BrN7O4
TargetHistone Methyltransferase,HDAC,Endogenous Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information