HDAC8/BRPF1-IN-1

SKU: orb1687867

Description

HDAC8/BRPF1-IN-1 (Compound 23a) is a dual inhibitor targeting human HDAC8 (IC50: 443 nM) and BRPF1 (Kd: 67 nM) with selectivity over HDAC1 and HDAC6. This compound serves as a chemical probe for epigenetic research, enabling the study of histone acetylation mechanisms in cancer and neurodevelopmental disease models.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2484255-85-6
• MW: 417.44
• Formula: C₁₉H₁₉N₃O₆S
• SMILES: CN1C=2C(=CC(NS(=O)(=O)C3=C(OC)C=CC(C(NO)=O)=C3)=CC2)C=C(C)C1=O
• Target: HDAC,Epigenetic Reader Domain,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162667811