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HDAC8-IN-15

SKU: orb3211090

Description

HDAC8-IN-15 is a selective HDAC8 inhibitor with an IC50 of 0.40 μM. It enhances the acetylation levels of the HDAC8 substrate SMC3 without altering the total protein levels of SMC3. HDAC8-IN-15 reduces cancer cell viability, inhibits colony formation, slows cell migration, induces apoptosis, and causes cell cycle arrest at the SubG1 phase. This compound is applicable in neuroblastoma research.

Images & Validation

Key Properties

TargetApoptosis,HDAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information