HDAC6-IN-76

SKU: orb3211487

Description

HDAC6-IN-76 (Compound G25) is a selective HDAC6 inhibitor with an IC50 of 12 nM. It induces autophagy in a p53-dependent manner and also promotes apoptosis in a p53-dependent way. Moreover, HDAC6-IN-76 exhibits anticancer activity against hematologic malignancies, including acute myeloid leukemia.

Key Properties

• CAS Number: 3110559-06-0
• MW: 460.52
• Formula: C₂₄H₃₂N₂O₇
• SMILES: C[C@@H]1[C@]2([C@]34[C@@](O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])(O[C@@H]1OCC=5N=C(/C=C/C(NO)=O)C=CC5)[H])[H]
• Target: Autophagy,HDAC,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Autophagy,HDAC,Apoptosis