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HDAC6-IN-61

SKU: orb3135279

Description

HDAC6-IN-61 (Compound 4e) is an HDAC6 inhibitor with an IC50 of 73 nM, demonstrating greater selectivity compared to other HDAC isomers. It also acts as an activator of GPR40. HDAC6-IN-61 can increase the acetylation of tubulin and phosphorylation levels of ERK. This compound is relevant for studying neuroinflammation, including Alzheimer's disease.

Research Area

Epigenetics & Chromatin, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

TargetHDAC,Microtubule Associated,ERK,GPCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information