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HDAC6-IN-47

SKU: orb3134489

Description

HDAC6-IN-47 (Compound S-29b) is an HDAC inhibitor with high affinity for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10, with Ki values of 60, 56, 162, 0.44, 362, and 849 nM, respectively. It induces hyperacetylation of tubulin in MV4-11 cells and inhibits their proliferation with an EC50 of 0.50 µM. HDAC6-IN-47 is applicable in leukemia research.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

FormulaC29H33N5O6
TargetHDAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information