HDAC6-IN-43

SKU: orb3134548

Description

HDAC6-IN-43 (compound 26) is a potent inhibitor of HDACs. This compound effectively inhibits various HDACs, notably HDAC1, HDAC2, and HDAC6, with an IC50 of less than 150 nM, and demonstrates particularly high sensitivity to HDAC6 with an IC50 of 11 nM. HDAC6-IN-43 is utilized in the study of autosomal dominant polycystic kidney disease (ADPKD).

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 3037978-19-8
• MW: 400.49
• Formula: C₂₁H₂₄N₂O₄S
• SMILES: O=C(NO)CCCCCCOC1=CC(=CC=C1OC)C2=NC=3C=CC=CC3S2
• Target: HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC