HDAC6-IN-34

SKU: orb2566129

Description

HDAC6-IN-34 (compound 21) is a potent and selective HDAC6 inhibitor (IC50 = 18 nM) that increases tubulin acetylation in lymphoma cells and reduces TNF-α in macrophages. It has demonstrated significant oral anti-arthritic activity in rat models, supporting its use in oncology and inflammation research.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1432508-73-0
• MW: 381.35
• Formula: C₁₈H₁₈F₃N₃O₃
• SMILES: C(N1C2=C(C(C(F)(F)F)=N1)C(=O)CC(C)(C)C2)C3=CC=C(C(NO)=O)C=C3
• Target: HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71526388