HDAC3-IN-T247

SKU: orb1703389

Description

HDAC3-IN-T247 is a selective and potent HDAC3 inhibitor with demonstrated anticancer and antiviral research applications. It induces dose-dependent NF-κB acetylation and inhibits proliferation in human colon cancer HCT116 cells, supporting its use in both in vitro and in vivo oncology studies.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology

Key Properties

• CAS Number: 1451042-18-4
• MW: 389.47
• Purity: 98.94% (May vary between batches)
• Formula: C₂₁H₁₉N₅OS
• SMILES: Nc1ccccc1NC(=O)c1ccc(cc1)-c1cn(CCc2ccsc2)nn1
• Target: Histone Demethylase|||Antiviral
• Solubility: DMSO:20 mg/mL (51.35 mM)

Bioactivity

• Target IC50:
  HDAC3:0.24 μM|HDAC6:>100 μM|HDAC8:>100 μM|HDAC4:>100 μM|HDAC1:19 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antiviral, Histone Demethylase, HistoneDemethylase, HDAC3 IN T 247, HDAC3 IN T247, HDAC3 IN T-247, HDAC3 inhibitor T 247, HDAC3 inhibitor T247, HDAC3 inhibitor T-247, HDAC3 inhibitor-T 247, HDAC3 inhibitor-T247, HDAC3 inhibitor-T-247, HDAC3INT 247, HDAC3-IN-T 247, HDAC3INT247, HDAC-3-IN-T247, HDAC3-IN-T247, HDAC3-IN-T-247, HDAC3INT-247, T247, T-247, T 247

Compound Identifiers

PubChem CID

71721946