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HDAC3-IN-7

SKU: orb3027917

Description

HDAC3-IN-7 (Compound 8ae) is a selective HDAC3 inhibitor with an IC50 value of 311 nM. It effectively induces the degradation of PD-L1 via a cathepsin B-mediated lysosomal pathway, demonstrating the ability to inhibit tumor cell proliferation, migration, and invasion. HDAC3-IN-7 holds potential for cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology

Images & Validation

Key Properties

FormulaC25H37N5O4S
TargetHDAC,PD-1/PD-L1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information