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HDAC3-IN-5

SKU: orb2664456

Description

HDAC3-IN-5 (9c) is a potent and selective HDAC3 inhibitor (IC50 = 4.2 nM). It induces apoptosis in MV4-11 cells in vitro and reduces anti-apoptotic protein expression, showing potential as a lead compound for research into overcoming Venetoclax resistance in hematological cancers.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

TargetApoptosis,HDAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information