HDAC3-IN-2

SKU: orb2277743

Description

HDAC3-IN-2 is a potent and selective HDAC3 inhibitor (IC50 = 14 nM) with anti-tumor activity against triple-negative breast cancer. It demonstrates cytotoxicity in 4T1 and MDA-MB-231 cells and shows in vivo efficacy by modulating histone acetylation, apoptosis, and proliferation markers in mouse models.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Key Properties

• MW: 315.37
• Formula: C₁₆H₂₁N₅O₂
• Target: HDAC,Histone Methyltransferase,Apoptosis,DNA/RNA Synthesis,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC,Histone Methyltransferase,Apoptosis,DNA/RNA Synthesis,Caspase