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HDAC1/CDK7-IN-1

SKU: orb1942539

Description

HDAC1/CDK7-IN-1 (compound 8e) is a dual inhibitor of CDK7 (IC50=893 nM) and HDAC1 (IC50=248 nM) that suppresses proliferation, induces cell cycle arrest and apoptosis, and inhibits migration in cancer cell lines like HCT-116, supporting oncology research and therapeutic development.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

CAS Number2987905-95-1
MW626.11
FormulaC33H32ClN7O4
SMILESO=C(NC=1C=CC=C(C1)NC=2N=CC(Cl)=C(N2)C3=CNC=4C=CC=CC43)C=5C=CC=C(C5)NC(=O)CCCCCCC(=O)NO
TargetApoptosis,HDAC,CDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information