HDAC-IN-54

SKU: orb3210976

Description

HDAC-IN-54 is an HDAC inhibitor with an IC50 of 25 nM for human HDAC1, 66 nM for HDAC2, 6.5 nM for HDAC3, and 281 nM for HDAC6. It induces acetylation of α-tubulin and histone H3. HDAC-IN-54 can synergize with cisplatin to induce apoptosis in cancer cells and is applicable in research related to head and neck cancer, ovarian cancer, and tongue squamous cell carcinoma.

Key Properties

• CAS Number: 2098896-13-8
• MW: 440.54
• Formula: C₂₄H₃₂N₄O₄
• SMILES: O=C(NO)CCCCCN(C(=O)C1=CC=C(C=C1)N(C)C)CC(=O)NCC=2C=CC=CC2
• Target: Apoptosis,HDAC,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,HDAC,Microtubule Associated