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HDAC-IN-100

SKU: orb3212268

Description

HDAC-IN-100 is a histone deacetylase inhibitor with IC50 values of 0.038 μM for HDAC1, 0.283 μM for HDAC2, and 0.586 μM for HDAC3. It functions as a chemosensitizer and apoptosis (apoptosis) inducer, activating caspase3/7 and counteracting Cisplatin resistance. HDAC-IN-100 exhibits antiproliferative effects in ovarian cancer and squamous carcinoma cells. It is valuable for research on ovarian cancer, squamous cell carcinoma, and Cisplatin-resistant squamous cell carcinoma.

Images & Validation

Key Properties

TargetCaspase,HDAC,Apoptosis
CAS Number2390474-88-9
MW535.64
FormulaC32H33N5O3
SMILESO=C(NC=1C=CC=CC1N)C2=CC=C(C=C2)CN(C(=O)C3=CC=C(C=C3)N(C)C)CC(=O)NCC=4C=CC=CC4

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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