HD-TAC7

SKU: orb1982871

Description

HD-TAC7 is a potent PROTAC-based degrader of HDAC1, HDAC2, and HDAC3, with respective IC50 values of 3.6 μM, 4.2 μM, and 1.1 μM. It reduces NF-κB p65 levels in RAW 264.7 macrophages and is a research tool for studying inflammatory diseases like asthma and COPD.

Research Area

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2978763-95-8
• MW: 657.65
• Purity: 99.70%
• Formula: C₃₃H₃₂FN₇O₇
• SMILES: O=C(NC1=CC=C(F)C=C1N)C2=CC=C(C=C2)NC(=O)CCCCNC(=O)CNC3=CC=CC=4C(=O)N(C(=O)C34)C5C(=O)NC(=O)CC5
• Target: PROTACs,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTACs,HDAC