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HCV-IN-50

SKU: orb3173827

Description

HCV-IN-50 (Compound 2) is a competitive and selective inhibitor of HCV NS5B RNA-dependent RNA polymerase. It exhibits an IC50 of 0.3 μM against the NS5B ΔC21 enzyme, demonstrating superior inhibitory potency compared to the ΔC55 enzyme. HCV-IN-50 possesses antiviral activity, effectively blocking replication of HCV subgenomic replicons, particularly mutant replicons.

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Key Properties

CAS Number303776-85-4
MW397.45
FormulaC20H19N3O4S
SMILESO=C1C(=C(O)C=2C=CC=CC2N1CC(C)C)C3=NS(=O)(=O)C=4C=CC=CC4N3
TargetDNA/RNA Synthesis,HCV Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

HCV-IN-50 (orb3173827)

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