HCN-IN-1

SKU: orb3210815

Description

HCN-IN-1 is a TLR4 inhibitor and a modulator of HCN2/HCN4 channels. It inhibits TLR4-mediated SEAP signaling activity and exerts its pharmacological effects by reducing HCN2 currents, altering their voltage-dependent activation and kinetics, and blocking HCN4 currents. HCN-IN-1 demonstrates analgesic, anti-inflammatory, and anti-anginal activities, making it applicable for research on inflammatory pain, neuropathic pain, heart failure, and inflammation.

Key Properties

• CAS Number: 2234283-04-4
• MW: 484.07
• Formula: C₂₈H₃₈ClN₃O₂
• SMILES: ClC=1C=CC=CC1CN2N=C(C(=C2C)CN(C)CC(O)CCOC3=CC=C(C=C3)C(C)(C)C)C
• Target: Phosphatase,TLR,Potassium Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Phosphatase,TLR,Potassium Channel