HCI-2184

SKU: orb1703390

Description

HCI-2184 is a dual inhibitor targeting AXL kinase and Nek2, developed to overcome bortezomib resistance in multiple myeloma. It has demonstrated efficacy in both in vitro cell-based assays and in vivo xenograft models, making it a valuable research tool for investigating drug-resistant cancer mechanisms.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1341200-61-0
• MW: 502.03
• Formula: C₂₃H₂₈ClN₇O₂S
• SMILES: S(N(C)C)(=O)(=O)C1=C(NC2=NC(NC3=CC=C(C=C3)N4CCN(C)CC4)=NC=C2Cl)C=CC=C1
• Target: MAPK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

70685611