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hCA/VEGFR-2-IN-5

SKU: orb3134852

Description

hCA/VEGFR-2-IN-5 (compound 9) is an indolinone phenylsulfonamide and a potential dual inhibitor of hCA IX/XII and VEGFR-2, which are associated with cancer. The compound has IC50 values of 0.38 μM for VEGFR-2, 40 nM for hCA IX, and 3.2 nM for hCA XII. It exhibits antitumor activity.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

FormulaC26H34N4O10S
TargetVEGFR,Carbonic Anhydrase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information