hCA/VEGFR-2-IN-4

SKU: orb2277828

Description

hCA/VEGFR-2-IN-4 (15b) is a dual-action indolinylbenzenesulfonamide inhibitor with potent activity against cancer-associated hCA IX/XII (Ki values in low nM range) and VEGFR-2 (IC50 = 0.811 µM). It demonstrates antiproliferative effects in breast cancer cell models, supporting its investigation in oncology research for targeting tumor hypoxia and angiogenesis.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• MW: 502.52
• Formula: C₂₂H₂₃FN₆O₅S
• Target: VEGFR,Carbonic Anhydrase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

VEGFR,Carbonic Anhydrase