hCAIX/XII-IN-6

SKU: orb1744630

Description

hCAIX/XII-IN-6 is a potent, orally bioavailable carbonic anhydrase inhibitor with high selectivity for tumor-associated isoforms hCA IX (Ki=4.1 nM) and XII (Ki=7.7 nM). It is used in rheumatoid arthritis research and has demonstrated efficacy in reducing disease severity in preclinical in vivo models of inflammation.

Research Area

Metabolism Research

Key Properties

• MW: 601.74
• Formula: C₂₆H₂₃N₃O₆S₄
• SMILES: COC1=C(C=CC(=C1)[N+](=O)[O-])CN(CCC2=CC=C(C=C2)S(=O)(=O)N)C(=O)C3=CC=C(C=C3)C4=CSSC4=S
• Target: Others,Carbonic Anhydrase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165412817