hCAII/XII-IN-1

SKU: orb2945372

Description

hCAII/XII-IN-1 (compound 4l) is a dual, nanomolar-potency inhibitor of human carbonic anhydrases XII and II, with Kᵢ values of 8.4 nM and 9.4 nM, respectively. It is a valuable research tool for investigating CA-mediated pH regulation in cancer cell proliferation and tumor progression in both in vitro and in vivo models.

Research Area

Metabolism Research

Key Properties

• MW: 500.547
• Formula: C₂₂H₂₀N₄O₆S₂
• SMILES: C1=CC=C(C(=C1)C2C=C(C(=O)N2C3=CC(=CC=C3)S(=O)(=O)N)NC4=CC(=CC=C4)S(=O)(=O)N)O
• Target: Carbonic Anhydrase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676866