hCAI/II-IN-7

SKU: orb2566138

Description

hCAI/II-IN-7 (Compound 1F) is a potent carbonic anhydrase inhibitor with Ki values of 23 nM for hCA-I, 44 nM for hCA-II, and 21 µM for bCA. This small molecule is a valuable research tool for studying CA-related pathologies, such as glaucoma and cancer, in both in vitro and cellular assay systems.

Research Area

Metabolism Research

Key Properties

• CAS Number: 14204-32-1
• MW: 334.19
• Purity: 99.75%
• Formula: C₁₄H₈BrNO₂S
• SMILES: O=C1C=2C(C(=O)N1SC3=CC=C(Br)C=C3)=CC=CC2
• Target: Carbonic Anhydrase
• Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (5.98 mM);DMSO:20 mg/mL (59.85 mM)

Bioactivity

• Target IC50:
  CA II (human):44 nM (Ki)|CA I (human):23 nM (Ki)|CA (bovine):20.57 μM (Ki)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56834079