HC-7366

SKU: orb2566187

Description

HC-7366 (GCN2 modulator-1) is an orally bioavailable, small-molecule activator of GCN2 kinase. It demonstrates antitumor activity by inducing integrated stress response pathways, leading to tumor growth inhibition in preclinical in vivo models, making it a valuable research tool for oncology and immunometabolism studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 2803470-63-3
• MW: 508.89
• Purity: 99.84%
• Formula: C₂₀H₁₅ClF₂N₆O₄S
• SMILES: O=C(NC)C=1N=CN2C=C(N=CC12)C3=C(F)C=CC(NS(=O)(=O)C4=CC(Cl)=CN=C4OC)=C3F
• Target: PERK
• Solubility: DMSO:20 mg/mL (39.3 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GCN2 modulator-1, HC7366

Compound Identifiers

PubChem CID

164593978