HC-258

SKU: orb2564303

Description

HC-258 is a covalent TEAD inhibitor that selectively targets Cys380, suppressing the transcription of downstream targets like CTGF and CYR61. It has demonstrated efficacy in inhibiting cell migration in MDA-MB-231 breast cancer cells in vitro, supporting its use in Hippo pathway and cancer biology research.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3056128-12-9
• MW: 324.42
• Formula: C₂₀H₂₄N₂O₂
• SMILES: O=C(C=C)NC1=CC=CC(=C1)NC=2C=CC=C(OCCCCC)C2
• Target: YAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HC258

Compound Identifiers

PubChem CID

169494206