HBV/HDV-IN-2

SKU: orb2564377

Description

HBV/HDV-IN-2 (Compound 143) is a small molecule inhibitor targeting hepatitis B virus (HBV), hepatitis D virus (HDV), and the PD-1/PD-L1 immune checkpoint. It demonstrates potent activity with an EC50 of 35 nM in T cell activation assays, supporting its utility in antiviral and immuno-oncology research.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 3034161-76-4
• MW: 714.25
• Formula: C₃₈H₄₄ClN₇O₅
• SMILES: ClC1=C(N=CC=C1C=2N=C(OC)C(CNC3CCN(C(C)=O)CC3)=CC2)C4=C(C)C(NC(=O)C5=CC(OC)=C(CN6C[C@H](O)CC6)C=N5)=CC=C4
• Target: PD-1/PD-L1,HBV

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171490025