HBV/HDV-IN-1

SKU: orb2564590

Description

HBV/HDV-IN-1 (Compound 122) is a small molecule inhibitor targeting hepatitis B virus (HBV), hepatitis D virus (HDV), and the PD-1/PD-L1 immune checkpoint. It demonstrates potent activity in cellular assays, with EC50 values of 8 nM for T cell activation and 35 nM for PD-L1 internalization, supporting its use in antiviral and immuno-oncology research.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 3034161-55-9
• MW: 761.70
• Formula: C₃₈H₄₂Cl₂N₈O₅
• SMILES: ClC1=C(N=CC=C1C=2N=C(OC)C(CNC[C@H]3NC(=O)CC3)=CC2)C4=C(Cl)C(NC(=O)C5=CC(OC)=C(CNC6CCN(C(C)=O)CC6)C=N5)=CC=C4
• Target: HBV,PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171490381