Hastatoside

SKU: orb1301520

Description

Hastatoside

Key Properties

• CAS Number: 50816-24-5
• MW: 404.37
• Purity: 99.90%
• Formula: C₁₇H₂₄O₁₁
• SMILES: [H][C@@]12[C@@H](C)CC(=O)[C@]1(O)C(=CO[C@H]2O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)OC
• Target: Others
• Solubility: DMSO:80 mg/mL (197.84 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.16 mM)

Bioactivity

• In Vivo:
  Herbal tea made from Verbena officinalis (V. officinalis) has traditionally been used for the treatment of insomnia and other nervous conditions. Examined the sleep-promoting activity of hastatoside, verbenalin, and verbascoside, which are the major iridoids (hastatoside and verbenalin) and polyphenol (verbascoside) components responsible for the pharmacological activity of V. officinalis, by electroencephalographic analysis of rats after oral administration of the compounds. Hastatoside (0.64 mmol/kg of body weight) and verbenalin (1.28 mmol/kg of body weight) increased the total time of non-rapid eye movement sleep during a 9-h period from 23.00 to 08.00 hours by 81% and 42%, respectively, with a lag time of about 3–5 h after the administration at 20.00 hours (lights-off time). Both compounds also increased the delta activity during non-rapid eye movement sleep. However, verbascoside had no effect on the amount of sleep. Therefore, hastatoside and verbenalin are major sleep-promoting components of V. officinalis.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Hastatoside, Inhibitor

Compound Identifiers

PubChem CID

92043450