Hamamelitannin

SKU: orb1297347

Description

Hamamelitannin, a quorum-sensing inhibitor extracted from witch hazel bark, exhibits cytotoxic and antibiofilm activity against Staphylococcus aureus. It potentiates antibiotic efficacy by disrupting peptidoglycan synthesis and reduces oxidative cell damage, making it a valuable tool for studying biofilm-related infections and antimicrobial resistance in vitro.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 469-32-9
• MW: 484.36
• Purity: 99.99% (May vary between batches)
• Formula: C₂₀H₂₀O₁₄
• SMILES: C(OC[C@@]([C@@H]([C@@H](COC(=O)C1=CC(O)=C(O)C(O)=C1)O)O)(C=O)O)(=O)C2=CC(O)=C(O)C(O)=C2
• Target: Antifection,Antibacterial
• Solubility: DMSO:20 mg/mL (41.29 mM)

Bioactivity

• In Vitro:
  Hamamelitannin has specific cytotoxic activity against colon cancer cells.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Hamamelitannin, Inhibitor, infections, inhibit, Bacterial, antibiotic, Antifection, cancer, cells, colon, cytotoxic, suppressor, quorum-sensing, peptidoglycan, TRAP

Compound Identifiers

PubChem CID

21145076