Hakin-1

SKU: orb3173108

Description

Hakin-1 is an inhibitor of the E3 ubiquitin ligase Hakai. It effectively blocks both overall ubiquitination mediated by Hakai and the specific ubiquitination of E-cadherin, thereby inhibiting the process of epithelial-mesenchymal transition (EMT). Hakin-1 can impede tumor progression and cancer metastasis and is utilized for research in colorectal cancer and other cancers.

Research Area

Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 346660-34-2
• MW: 385.35
• Formula: C₁₆H₁₁N₅O₅S
• SMILES: O=C(O)C1=CC=C(C=C1)N2N=NN=C2SCC(=O)C3=CC=C(C=C3)N(=O)=O
• Target: Cadherin,E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Cadherin,E1/E2/E3 Enzyme