hAChE-IN-8

SKU: orb3134223

Description

hAChE-IN-8 (Compound S-12) is an orally active and selective inhibitor of hAChE, with an IC50 of 0.486 μM. It also inhibits BACE-1 with an IC50 of 0.542 μM, but shows negligible inhibition of Dyrk1A (IC50>10 μM). This compound reduces Aβ aggregation, exhibits good blood-brain barrier penetration, and is primarily used in Alzheimer's disease research.

Research Area

Cell Biology, Neuroscience, Signal Transduction

Key Properties

• Formula: C₂₅H₂₂N₄O₄
• Target: DYRK,Cholinesterase (ChE)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DYRK,Cholinesterase (ChE)