HA-100

SKU: orb1299628

Description

HA-100 is a cell-permeable, potent inhibitor of protein kinases such as PKA and PKC. It is widely used in biochemical and cellular research to investigate kinase signaling pathways in both in vitro enzymatic assays and in vivo model systems.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 84468-24-6
• MW: 277.34
• Purity: 99.69% (May vary between batches)
• Formula: C₁₃H₁₅N₃O₂S
• SMILES: O=S(=O)(N1CCNCC1)c1cccc2cnccc12
• Target: PKA,ROCK,PKC,Myosin
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.42 mM);DMSO:150 mg/mL (540.85 mM)

Bioactivity

• Target IC50:
  MLCK:240 μM |MLCK:61 μM (Ki)|PKA:8 μM |PKG:4 μM |PKC:12 μM|PKC:6.5 μM (Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, HA100, HA-100, HA 100, Myosin, inhibit, kinase, MLCK, protein, Protein kinase A, Protein kinase C, Rho-associated protein kinase, Rho-associated kinase, Rho-kinase, ROK, ROCK, PKG, PKC, PKA

Compound Identifiers

PubChem CID

3545