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H3B-6545

SKU: orb1709500

Description

H3B-6545 is an orally bioavailable, selective estrogen receptor covalent antagonist (SERCA) for research. It is utilized in studies of ERα-positive, HER2-negative metastatic breast cancer, demonstrating activity in both in vitro cellular assays and in vivo xenograft models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2052130-80-8
MW567.58
FormulaC30H29F4N5O2
SMILESC(=C(\CC(F)(F)F)/C1=CC=CC=C1)(\C=2C=C3C(=CC2)NN=C3F)/C=4C=CC(OCCNC/C=C/C(N(C)C)=O)=NC4
TargetEstrogen/progestogen Receptor,Estrogen Receptor/ERR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information