H-Ras

SKU: orb533497

Description

Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). Suitable as a substrate for farnesyltransferase. Protein preparation is 98% GDP-and 2% GTP-loaded, measured by HPLC.

Research Area

Signal Transduction

Key Properties

• Source: E. coli
• Biological Origin: human
• Biological Activity: GTPγS binding: > 750 mmol/mol.
• MW: Theoretical MW: 21.3 kDa (189 amino acids)
• Purity: > 90% (SDS-PAGE)

Storage & Handling

• Storage: store at -80 °C
• Form/Appearance: liquid (Supplied in 25 mM HEPES pH 7.2, 40 mM NaCl, 3 mM DTT, 2 mM MgCl 2and 0.01 mM GDP)
• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Alternative Names

Harvey rat sarcoma viral oncogene homolog, human, recombinant, E. coli