h-NTPDase-IN-4

SKU: orb1819007

Description

h-NTPDase-IN-4 is a potent pan-inhibitor of human NTPDases 1, 2, 3, and 8, exhibiting IC50 values of 3.58 μM, 10.21 μM, 0.13 μM, and 13.57 μM, respectively. This compound is a valuable research tool for studying purinergic signaling in both cellular and animal models of inflammation, thrombosis, and cancer.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2939933-09-0
• MW: 560.36
• Purity: 99.97% (May vary between batches)
• Formula: C₂₂H₈F₁₂N₂S
• SMILES: C(F)(F)(F)C=1C=C(C2=C3C(C(=CS3)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=NC=N2)C=C(C(F)(F)F)C1
• Target: Phosphatase
• Solubility: DMF:56.04 mg/mL (100.01 mM)

Bioactivity

• Target IC50:
  NTPDase2 (human):10.21 μM|NTPDase8 (human):13.57 μM|NTPDase1 (human):3.58 μM|NTPDase3 (human):0.13 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Phosphatase, hNTPDaseIN4, h-NTPDase-IN-4

Compound Identifiers

PubChem CID

168510598